Description

1-Bromo-4-Methoxybutane is a versatile alkylating agent and a key organic building block characterized by its bromine and ether functionalities. This compound is valued for its reactivity in nucleophilic substitution and coupling reactions, enabling the synthesis of more complex molecular architectures. It is primarily sought after by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing intermediates and active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing methoxybutyl side chains.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators requiring specific alkoxyalkyl structures.
• Organic Synthesis Reagent: Serves as an alkylating agent in various carbon-carbon and carbon-heteroatom bond-forming reactions under basic conditions.
• Liquid Crystal & Material Science: Employed in the research and development of advanced organic materials, including liquid crystal compounds and polymers.
• Flavor & Fragrance Industry: Acts as a precursor for synthesizing specific ethers used in fragrance compositions.
• Cross-Coupling Reactions: Functions as a substrate in metal-catalyzed cross-coupling reactions, such as Suzuki or Negishi couplings, to form complex biaryl systems.

Basic Information

Product Name	1-Bromo-4-Methoxybutane
CAS No.	4457-67-4
Molecular Formula	C5H11BrO
Molecular Weight	167.04 g/mol
Synonyms	4-Methoxybutyl bromide; 4-Bromo-1-methoxybutane; 1-Methoxy-4-bromobutane; Butane, 1-bromo-4-methoxy-; (4-Bromobutyl) methyl ether; 4-Methoxybutylbromide; 4-Bromobutyl methyl ether; 1-Bromo-4-methoxy-butane
EINECS	224-707-6

Quality Control

Our 1-Bromo-4-Methoxybutane is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including GC, NMR, and purity assays, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing specific results for identity, purity, and impurities is provided with each shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Refractive Index (n20D)	1.4520 - 1.4560
Density (g/mL, 20°C)	1.280 - 1.320
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.