Description

2-Phenylethanethiol is a versatile organosulfur compound characterized by its distinctive thiol functional group attached to a phenethyl moiety. This structure makes it a valuable building block and intermediate in the synthesis of complex molecules, particularly in the pharmaceutical and fragrance industries. Its primary utility lies in its ability to introduce sulfur-containing functional groups or act as a precursor for heterocyclic compounds. Key industrial users include R&D laboratories, fine chemical manufacturers, and producers of agrochemicals, flavors, and pharmaceuticals seeking reliable, high-purity intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of various active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring thioether or disulfide linkages.
• Flavor & Fragrance Ingredient: Used in the creation of specific savory, meaty, or roasted aroma notes due to its sulfurous character, often in trace amounts for flavor enhancement.
• Agrochemical Synthesis: Acts as an intermediate in the production of certain pesticides, herbicides, and fungicides where the thiol group is integral to biological activity.
• Polymer & Material Science: Employed as a chain-transfer agent or modifier in polymerization reactions and in the surface functionalization of materials.
• Organic Synthesis Reagent: A valuable reagent for introducing the phenethylthio group or for use in nucleophilic substitution and addition reactions in research and development.
• Catalyst & Ligand Preparation: Utilized in the preparation of metal-complexing ligands or catalysts for specialized chemical transformations.

Basic Information

Product Name	2-Phenylethanethiol
CAS No.	4410-99-5
Molecular Formula	C8H10S
Molecular Weight	138.23 g/mol
Synonyms	Phenethyl mercaptan; β-Phenylethyl mercaptan; 2-Phenylethylthiol; (2-Mercaptoethyl)benzene; Benzeneethanethiol; Phenylethylthiol; Thiophenethyl alcohol; 2-Thiophenethyl alcohol
EINECS	224-555-1

Quality Control

Our 2-Phenylethanethiol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting identity, assay, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for critical applications in pharmaceutical and fine chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C) under an inert atmosphere (e.g., nitrogen) to minimize oxidation. Keep away from heat, sparks, open flames, and strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Refractive Index (n20D)	1.555 - 1.565
Density (20°C)	1.020 - 1.040 g/mL
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.