Description

1-Phenyl-But-3-Yn-2-Ol is a versatile chiral building block featuring both a phenyl group and a terminal alkyne functionality. This unique molecular structure makes it a valuable intermediate in organic synthesis, particularly for constructing complex molecules through reactions like Sonogashira coupling and nucleophilic additions. It is primarily sought after by research institutions and pharmaceutical companies for applications in medicinal chemistry, agrochemical development, and advanced material science.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the research and production of novel pesticides and herbicides.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis.
• Material Science Research: Building block for polymers and advanced organic materials with specific optical or electronic properties.
• Academic and R&D Laboratories: Essential reagent for methodological studies in synthetic organic chemistry.
• Fine Chemical Production: Intermediate in the multi-step synthesis of complex fragrance and flavor compounds.

Basic Information

Product Name	1-Phenyl-But-3-Yn-2-Ol
CAS No.	4378-23-8
Molecular Formula	C10H10O
Molecular Weight	146.19 g/mol
Synonyms	1-Phenyl-3-butyn-2-ol; 3-Butyn-2-ol, 1-phenyl-; 1-Phenylbut-3-yn-2-ol; 2-Butyn-1-ol, 4-phenyl-; 4-Phenyl-2-butyn-1-ol; (RS)-1-Phenyl-3-butyn-2-ol; (±)-1-Phenyl-3-butyn-2-ol; Phenylbutynol
EINECS	Contact for details

Quality Control

Our 1-Phenyl-But-3-Yn-2-Ol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications and can accommodate custom purity requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.