Description

2-Chloro-4-Cyanoquinoline is a versatile and high-value heterocyclic building block in organic synthesis. Its molecular structure, featuring both a chloro and a cyano substituent, makes it a critical intermediate for constructing more complex pharmacologically active compounds. This compound is essential for research and development chemists and manufacturers in the pharmaceutical and agrochemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various quinoline-based drug candidates, including kinase inhibitors and antimicrobial agents.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides that leverage the quinoline scaffold for bioactivity.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Dye and Pigment Manufacturing: Acts as an intermediate in the production of specialized quinoline dyes and colorants.
• Academic & Contract Research: Utilized in university and CRO laboratories for method development and exploratory synthesis in medicinal chemistry projects.
• Custom Synthesis: A starting material for the contract manufacturing of proprietary compounds and advanced intermediates for clients.

Basic Information

Product Name	2-Chloro-4-Cyanoquinoline
CAS No.	4366-88-5
Molecular Formula	C10H5ClN2
Molecular Weight	188.61 g/mol
Synonyms	4-Cyano-2-chloroquinoline; 2-Chloro-4-quinolinecarbonitrile; 2-Chloroquinoline-4-carbonitrile; Quinoline, 2-chloro-4-cyano-; 2-Chloro-4-cyanquinolin; 2-Chlor-4-cyanochinolin
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Cyanoquinoline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.