Description

2-Bromomethyl-1,3-dioxolane is a versatile brominated acetal derivative, primarily valued as a key synthetic intermediate and protecting group reagent in advanced organic synthesis. Its unique structure allows for the selective introduction of functional groups, making it crucial for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly in constructing heterocyclic compounds and nucleoside analogs.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and plant growth regulators.
• Polymer Chemistry: Acts as a functional monomer or cross-linking agent in the production of specialty polymers and resins.
• Organic Synthesis Reagent: Employed as a protecting group for aldehydes and ketones, and as an alkylating agent in multi-step synthetic routes.
• Material Science Research: Utilized in the development of advanced organic electronic materials and liquid crystals.
• Chemical Biology: Applied in the synthesis of probes and labeled compounds for biochemical and medicinal research.

Basic Information

Product Name	2-Bromomethyl-1,3-Dioxolane
CAS No.	4360-63-8
Molecular Formula	C4H7BrO2
Molecular Weight	167.00 g/mol
Synonyms	2-(Bromomethyl)-1,3-dioxolane; 1,3-Dioxolane, 2-(bromomethyl)-; Bromomethyl dioxolane; 2-Bromomethyl-1,3-dioxacyclopentane; α-Bromoacetaldehyde ethylene acetal; Acetaldehyde, bromo-, cyclic ethylene acetal; (2-Bromo-1,3-dioxolan-4-yl)methane (incorrect but sometimes used); Bromoacetaldehyde ethylene acetal
EINECS	224-456-6

Quality Control

Our 2-Bromomethyl-1,3-dioxolane is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chromatography (GC/HPLC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Total impurities ≤ 3.0%
Density (20°C)	1.50 - 1.60 g/mL
Refractive Index (n20D)	1.470 - 1.480

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.