Description

tert-Butoxyisopropoxymethane is a specialized acetal compound, CAS NO 4346-01-4, valued for its role as a versatile protecting group reagent and solvent in advanced organic synthesis. Its structure offers unique reactivity and selectivity, making it a critical component for chemists developing complex molecules. This high-purity chemical is essential for research and production in the pharmaceutical, agrochemical, and fine chemical industries where precise control over reaction pathways is required.

Application

• As a protecting group reagent for aldehydes and ketones in multi-step organic synthesis.
• Use as a specialty solvent or co-solvent in sensitive reactions requiring anhydrous conditions.
• Intermediate in the synthesis of pharmaceutical active ingredients (APIs) and complex natural products.
• Precursor for the preparation of other functionalized ethers and acetals.
• Component in catalyst systems and ligand synthesis for metal-catalyzed reactions.
• Used in agrochemical research for the development of novel pesticides and herbicides.
• Application in material science for the surface modification of polymers and coatings.

Basic Information

Product Name	tert-Butoxyisopropoxymethane
CAS No.	4346-01-4
Molecular Formula	C8H18O2
Molecular Weight	146.23 g/mol
Synonyms	1-(tert-Butoxy)-2-methoxypropane; 2-Methoxy-1-(tert-butoxy)propane; 1-tert-Butoxy-2-methoxypropane; tert-Butyl isopropyl acetal; Acetaldehyde tert-butyl isopropyl acetal; Isopropoxymethyl tert-butyl ether
EINECS	Contact for details

Quality Control

Our tert-Butoxyisopropoxymethane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including GC, NMR, and Karl Fischer titration, to confirm identity, potency, and the absence of critical impurities. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat and ignition sources. Due to its highly volatile and easily oxidized nature, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep container tightly sealed when not in use to prevent evaporation and moisture ingress.

Specification

Item	Specification
Appearance	Colorless clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Refractive Index (n20/D)	1.398 - 1.402
Density (g/mL at 20°C)	0.80 - 0.82

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.