Description

5-Chloro-1,2-Benzisothiazol-3(2H)-One is a versatile heterocyclic organic compound that serves as a key intermediate and active moiety in advanced chemical synthesis. Its value lies in its potent biological activity, making it a critical building block for the development of high-performance products. This compound is essential for manufacturers and R&D teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel antibacterial, antifungal, and anti-inflammatory agents, leveraging its benzisothiazolone core structure.
• Agrochemical Synthesis: Used in the development of next-generation fungicides and herbicides, where its chlorinated benzisothiazolone scaffold provides potent biocidal activity.
• Polymer Stabilizer & Additive: Acts as a stabilizer in polymer formulations to prevent degradation, or as a key component in creating functional materials.
• Research & Development: Serves as a fundamental building block in medicinal chemistry and material science research for exploring new chemical entities and properties.
• Biocide Formulation: Incorporated into industrial biocides, preservatives, and antimicrobial coatings for materials protection.
• Dye & Pigment Intermediate: Utilized in the synthesis of specialized dyes and organic pigments due to its heterocyclic structure.

Basic Information

Product Name	5-Chloro-1,2-Benzisothiazol-3(2H)-One
CAS No.	4337-43-3
Molecular Formula	C7H4ClNOS
Molecular Weight	185.63 g/mol
Synonyms	5-Chloro-1,2-benzisothiazolin-3-one; 5-Chloro-3H-1,2-benzisothiazol-3-one; 5-Chloro-1,2-benzisothiazol-3-one; 5-Chloro-2,1-benzisothiazol-3(2H)-one; 5-Chlorobenzisothiazolinone; 5-Chloro-1,2-benzisothiazolin-3-one; 5-Chloro-3-hydroxy-1,2-benzisothiazole; CBIT
EINECS	224-411-6

Quality Control

Our 5-Chloro-1,2-Benzisothiazol-3(2H)-One is produced under a stringent quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent chemical identity. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at ambient temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	156 - 160 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.