Description

1-O,2-O:3-O,4-o-Diisopropylidene-5,6-Dideoxy-5,6-Didehydro-D-Mannitol is a high-purity, protected sugar derivative, also known as a diacetonide, which serves as a crucial chiral building block and synthetic intermediate. Its value lies in its ability to provide a rigid, protected framework for the stereoselective synthesis of complex molecules, ensuring high optical purity in the final products. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require advanced intermediates for developing active pharmaceutical ingredients (APIs), chiral ligands, and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of nucleoside analogs, antiviral drugs, and other bioactive molecules.
• Asymmetric Catalysis: Used in the preparation of chiral ligands and catalysts for enantioselective synthesis.
• Carbohydrate Chemistry Research: Serves as a protected starting material for the synthesis of complex sugars, glycomimetics, and glycoconjugates.
• Agrochemical Synthesis: Intermediate in the production of chiral pesticides and herbicides.
• Fine Chemical Production: Building block for flavors, fragrances, and other high-value specialty chemicals requiring specific stereochemistry.
• Academic & R&D: A valuable reagent for methodological development in organic synthesis and medicinal chemistry.

Basic Information

Item	Detail
Product Name	1-O,2-O:3-O,4-o-Diisopropylidene-5,6-Dideoxy-5,6-Didehydro-D-Mannitol
CAS No.	4239-90-1
Molecular Formula	C12H18O4
Molecular Weight	226.27 g/mol
Synonyms	1,2:3,4-Di-O-isopropylidene-5,6-dideoxy-5,6-didehydro-D-mannitol; D-Mannitol Diacetonide; 5,6-Dideoxy-1,2:3,4-di-O-isopropylidene-5,6-didehydro-D-mannitol; 1,2:3,4-Di-O-isopropylidene-5,6-didehydro-5,6-dideoxy-D-mannitol; Diacetone D-Mannitol; 1,2:3,4-Diisopropylidene-D-mannitol; 5,6-Didehydro-5,6-dideoxy-1,2:3,4-di-O-isopropylidene-D-mannitol
EINECS	Contact for details

Quality Control

Our 1-O,2-O:3-O,4-o-Diisopropylidene-5,6-Dideoxy-5,6-Didehydro-D-Mannitol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure compliance with high-purity standards suitable for research and synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.