Description

(25R)-12β-Hydroxy-5α-Spirostan-3-One CAS NO 4235-32-9 is a high-purity steroidal sapogenin derivative, serving as a critical advanced intermediate in organic synthesis. Its defined stereochemistry and functional groups make it a valuable building block for the research and development of novel pharmaceutical compounds and bioactive molecules. This compound is primarily utilized by R&D laboratories and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for the synthesis of steroid-based drugs and other specialized chemical entities.

Application

• Pharmaceutical Intermediate: Key starting material or advanced intermediate in the synthesis of steroid-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or precursor in academic and industrial research exploring steroid metabolism and receptor interactions.
• Fine Chemical Synthesis: Serves as a chiral building block for constructing complex molecules in custom synthesis and process development.
• Hormone Analog Development: A foundational compound for research into new therapeutic agents targeting endocrine pathways.
• Natural Product Chemistry: Used in the semi-synthesis or structural modification of other naturally occurring steroidal compounds.

Basic Information

Product Name	(25R)-12β-Hydroxy-5α-Spirostan-3-One
CAS No.	4235-32-9
Molecular Formula	C27H42O4
Molecular Weight	430.63 g/mol
Synonyms	12β-Hydroxytigogenone; (25R)-12β-Hydroxy-5α-spirostan-3-one; 12β-Hydroxy-5α-spirostan-3-one; Tigogenone, 12β-hydroxy-; 3-Oxo-12β-hydroxy-(25R)-5α-spirostane; 5α-Spirostan-3-one, 12β-hydroxy-, (25R)-
EINECS	Contact for details

Quality Control

Our (25R)-12β-Hydroxy-5α-Spirostan-3-One is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and specific tests for related substances. We provide full traceability and Certificates of Analysis (COA) are available for all shipments to ensure compliance with your research and manufacturing specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Specific Rotation	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.