Description

8-Methyl-8-Azabicyclo[4.3.1]Decan-10-One CAS NO 4146-36-5 is a specialized nitrogen-containing bicyclic ketone, serving as a high-value advanced pharmaceutical intermediate and a versatile organic synthesis building block. Its unique bridged-ring structure makes it a critical precursor for developing complex molecules with targeted biological activity. This compound is essential for R&D and production teams in the pharmaceutical, agrochemical, and fine chemical sectors seeking to innovate new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of tropane alkaloid derivatives and other bioactive nitrogen heterocycles.
• Agrochemical Synthesis: Building block for novel pesticides and herbicides requiring complex, rigid molecular frameworks.
• Catalyst Ligand Development: Used to create novel chiral ligands for asymmetric catalysis in fine chemical production.
• Medicinal Chemistry Research: Core scaffold for drug discovery programs targeting neurological and other therapeutic areas.
• Fine Chemical Production: Intermediate in the manufacture of specialty chemicals, flavors, and fragrances.
• Academic & Industrial R&D: Serves as a model compound for studying reaction mechanisms and developing new synthetic methodologies.

Basic Information

Item	Details
Product Name	8-Methyl-8-Azabicyclo[4.3.1]Decan-10-One
CAS No.	4146-36-5
Molecular Formula	C10H17NO
Molecular Weight	167.25 g/mol
Synonyms	8-Methyl-8-azabicyclo[4.3.1]decan-10-one; 8-Methyl-8-azabicyclo[4.3.1]decan-10-one; 8-Methyl-8-azabicyclo[4.3.1]decan-10-one (8-Methylgranatan-10-one); 8-Methylgranatan-10-one; Granatan-10-one, 8-methyl-; 8-Methyl-8-azabicyclo[4.3.1]decanone; 8-Methyl-8-azabicyclo[4.3.1]decan-10-on (German); 8-Methyl-8-azabicyclo[4.3.1]decan-10-one (8-Methylgranatan-10-one)
EINECS	Contact for details

Quality Control

Our 8-Methyl-8-Azabicyclo[4.3.1]Decan-10-One is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC and GC analysis, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing identity, assay, and impurity profiles to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.