Description

Ethyl 1-Thio-α-D-Glucofuranoside is a specialized carbohydrate derivative, specifically a thioglycoside, where a sulfur atom replaces the oxygen in the glycosidic linkage. This structural modification makes it a valuable intermediate and building block in synthetic organic chemistry, particularly for the preparation of complex glycoconjugates and glycomimetics. It is primarily utilized by research institutions and pharmaceutical companies engaged in carbohydrate chemistry, medicinal chemistry, and the development of glycosidase inhibitors or novel bioactive compounds.

Application

• Glycosylation Reagent: Serves as a key thioglycosyl donor in the stereoselective synthesis of oligosaccharides and complex glycans.
• Medicinal Chemistry Intermediate: Used in the research and development of glycosidase inhibitors for potential therapeutic applications.
• Glycomimetic Synthesis: Acts as a precursor for creating stable glycomimetics that mimic natural carbohydrates.
• Bioconjugation: Employed in the preparation of glycoconjugates for biochemical studies and diagnostic applications.
• Chemical Biology Probe Development: Utilized as a building block for synthesizing probes to study carbohydrate-protein interactions.
• Academic & Industrial Research: A fundamental reagent for synthetic methodology development in carbohydrate chemistry laboratories.

Basic Information

Product Name	Ethyl 1-Thio-α-D-Glucofuranoside
CAS No.	4137-33-1
Molecular Formula	C8H16O5S
Molecular Weight	224.27 g/mol
Synonyms	Ethyl 1-Thio-α-D-glucofuranoside; 1-S-Ethyl-1-thio-α-D-glucofuranose; α-D-Glucofuranoside, ethyl 1-thio-; Ethyl α-D-thioglucofuranoside; 1-Thioethyl-α-D-glucofuranoside; Ethyl α-thioglucofuranoside; SEt-α-D-Glcf
EINECS	223-945-7

Quality Control

Our Ethyl 1-Thio-α-D-Glucofuranoside is produced under strict quality management protocols. Each batch is characterized and tested to ensure identity, purity, and consistency, meeting the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and identification results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation [α]20/D	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.