Description

4-Hydroxy-Benzocyclobutene is a high-purity, specialized organic compound featuring a unique strained cyclobutene ring fused to a phenolic moiety. This distinct structure makes it a valuable and versatile chemical intermediate for advanced synthesis in pharmaceutical and material science research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced polymer industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring strained ring systems or specific phenolic functionalities.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and organometallic chemistry.
• Advanced Material Precursor: Employed in the development of specialty polymers, resins, and organic electronic materials due to its rigid, fused-ring structure.
• Organic Synthesis Research: A valuable reagent for studying ring-opening and functionalization reactions of strained hydrocarbon systems in academic and industrial laboratories.
• Fine Chemical Production: Intermediate in the multi-step synthesis of complex fragrances, dyes, and other high-value fine chemicals.

Basic Information

Product Name	4-Hydroxy-Benzocyclobutene
CAS No.	4082-20-6
Molecular Formula	C8H8O
Molecular Weight	120.15 g/mol
Synonyms	4-Hydroxybicyclo[4.2.0]octa-1,3,5-triene; Benzocyclobuten-4-ol; 4-Benzocyclobutenol; 1,2-Dihydro-4-hydroxycyclobutabenzene; 4-OH-BCB; BCB-4-ol; Hydroxybenzocyclobutene
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-Benzocyclobutene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material is suitable for demanding research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.