Description

(S)-(+)-Phenylsuccinic Acid CAS NO 4036-30-0 is a high-purity, single-enantiomer chiral building block of significant importance in asymmetric synthesis. Its value lies in its utility as a versatile intermediate for constructing complex molecules with defined stereochemistry, which is critical for developing active pharmaceutical ingredients (APIs) and advanced materials. This product is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, optically pure starting materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of enantiomerically pure drugs, particularly for central nervous system (CNS) agents and enzyme inhibitors.
• Asymmetric Catalyst Ligand Precursor: Used to develop and synthesize novel chiral ligands for transition metal catalysis in stereoselective reactions.
• Agrochemical Synthesis: Serves as a building block for creating chiral active ingredients in herbicides and fungicides with improved efficacy and environmental profile.
• Fine Chemical & Specialty Material Production: Employed in the manufacture of liquid crystals, polymers, and other advanced materials where chirality dictates functional properties.
• Academic & Industrial R&D: A valuable tool for methodological development in organic synthesis and for exploring new chemical entities in discovery chemistry.
• Resolution Agent: Can be utilized as a chiral resolving agent for the separation of racemic mixtures of amines or other basic compounds.

Basic Information

Product Name	(S)-(+)-Phenylsuccinic Acid
CAS No.	4036-30-0
Molecular Formula	C10H10O4
Molecular Weight	194.18 g/mol
Synonyms	(S)-(+)-2-Phenylsuccinic Acid; (S)-2-Phenylbutanedioic Acid; (S)-α-Phenylsuccinic Acid; L-Phenylsuccinic Acid; (+)-Phenylsuccinic Acid; (2S)-2-Phenylbutanedioic Acid; Phenylsuccinic Acid, (S)-(+)-; Butanedioic acid, 2-phenyl-, (2S)-
EINECS	223-726-2

Quality Control

Our (S)-(+)-Phenylsuccinic Acid is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for chiral synthesis. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided and available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	166 - 170 °C
Loss on Drying	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.