Description

1,2,3,4-Di-o-Isopropylidene-α-D-Fucopyranose is a high-purity, protected sugar derivative that serves as a critical chiral building block and synthetic intermediate. Its value lies in providing a chemically stable scaffold for the stereoselective synthesis of complex bioactive molecules. This compound is essential for research and production in the pharmaceutical, biotechnology, and fine chemical industries, where precise control over molecular architecture is paramount.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of nucleoside analogs, antiviral agents, and other active pharmaceutical ingredients (APIs).
• Glycochemistry & Glycobiology Research: Used to construct complex oligosaccharides, glycoconjugates, and glycomimetics for biological studies and drug discovery.
• Carbohydrate Chemistry: Fundamental building block for the preparation of modified sugars and deoxy sugars with specific stereochemistry.
• Fine Chemical Synthesis: Employed in the production of specialty chemicals, flavors, fragrances, and advanced materials requiring chiral purity.
• Process Development: Serves as a standard or starting material in route scouting and optimization for scalable manufacturing processes.

Basic Information

Product Name	1,2,3,4-Di-o-Isopropylidene-α-D-Fucopyranose
CAS No.	4026-27-1
Molecular Formula	C12H20O5
Molecular Weight	244.28 g/mol
Synonyms	1,2:3,4-Di-O-Isopropylidene-α-D-Fucopyranose; α-D-Fucopyranose, 1,2:3,4-bis-O-(1-methylethylidene)-; Di-O-isopropylidene-α-D-fucose; 1,2:3,4-Di-O-isopropylidene-α-D-fucopyranose; 1,2:3,4-Di-O-(1-methylethylidene)-α-D-fucopyranose; 1,2:3,4-Diisopropylidene-α-D-fucopyranose; Protected D-Fucose Derivative
EINECS	223-702-5

Quality Control

Our 1,2,3,4-Di-o-Isopropylidene-α-D-Fucopyranose is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR) to ensure it meets the stringent requirements for synthetic applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when necessary to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]²⁰D	-80° to -90° (c=1 in CHCl₃)
Melting Point	105°C - 110°C
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.