Description

(2R)-2-Hydroxy-2-(2-Methoxyphenyl)Acetic Acid is a high-purity chiral building block and intermediate of significant importance in asymmetric synthesis. Its value lies in its defined stereochemistry, which is critical for producing enantiomerically pure compounds with targeted biological activity. This product is essential for research and development laboratories and production facilities in the pharmaceutical and fine chemical sectors, particularly for synthesizing active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of enantiomerically pure Active Pharmaceutical Ingredients (APIs), especially for central nervous system (CNS) and cardiovascular drugs.
• Asymmetric Catalyst Ligand Precursor: Used in the development and preparation of chiral ligands for metal-catalyzed asymmetric reactions, enhancing selectivity and yield.
• Fine Chemical Synthesis: Serves as a versatile building block for creating complex organic molecules with specific optical activity in agrochemical and specialty chemical research.
• Academic & Industrial R&D: Employed in methodological studies and process development for new synthetic routes requiring high stereochemical fidelity.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method validation in chiral separation techniques like HPLC.

Basic Information

Product Name	(2R)-2-Hydroxy-2-(2-Methoxyphenyl)Acetic Acid
CAS No.	4023-92-1
Molecular Formula	C9H10O4
Molecular Weight	182.17 g/mol
Synonyms	(R)-(-)-O-Methylmandelic Acid; (R)-2-Hydroxy-2-(2-methoxyphenyl)acetic Acid; (R)-(-)-2-Methoxymandelic Acid; (2R)-2-Hydroxy-2-(2-methoxyphenyl)ethanoic Acid; (R)-O-Methylmandelsäure; (R)-2-Methoxy-2-phenylglycolic Acid; (R)-α-Hydroxy-2-methoxyphenylacetic Acid; L-(-)-O-Methylmandelic Acid
EINECS	Contact for details

Quality Control

Our (2R)-2-Hydroxy-2-(2-Methoxyphenyl)Acetic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for pharmaceutical and advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.