Description

Acetic Acid (Chloroacetic)Anhydride is a specialized acylating agent and reactive chemical intermediate. This compound is valued for its ability to introduce the chloroacetyl functional group, a key building block in the synthesis of more complex molecules. It is primarily required by manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for the production of active ingredients and advanced intermediates.

Application

• Pharmaceutical Synthesis: Key intermediate in the production of active pharmaceutical ingredients (APIs), particularly for antibiotics and other chlorinated compounds.
• Agrochemical Manufacturing: Used in the synthesis of herbicides, pesticides, and plant growth regulators.
• Fine Chemical Production: Serves as a versatile acylating agent for creating specialty chemicals, dyes, and pigments.
• Polymer Modification: Employed to introduce reactive chloroacetyl groups into polymer chains for further functionalization.
• Bioconjugation & Proteomics: Useful in biochemical research for labeling proteins and other biomolecules.
• Organic Synthesis Reagent: A crucial reagent for Friedel-Crafts acylation and other condensation reactions in laboratory and industrial settings.

Basic Information

Product Name	Acetic Acid (Chloroacetic)Anhydride
CAS No.	4015-58-1
Molecular Formula	C4H4Cl2O3
Molecular Weight	170.98 g/mol
Synonyms	Chloroacetic Anhydride; Chloroacetic Acid Anhydride; Bis(chloroacetyl) Oxide; 2-Chloroacetic Anhydride; Dichloroacetic Anhydride (ambiguous, but common); Acetic Acid, Chloro-, Anhydride; Acetyl Chloride, Chloro- (oligomer); Chloroacetyl Anhydride
EINECS	223-677-8

Quality Control

Our Acetic Acid (Chloroacetic)Anhydride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the stringent requirements of industrial and research applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed to prevent decomposition. Recommended storage temperature is 2-8°C for long-term stability, though short-term storage at controlled room temperature (15-25°C) is acceptable for in-process materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Chloroacetic Acid Content	≤ 1.5%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.