Description

(S)-1,2,3,4-Tetrahydro-4-Oxo-2-Quinolinecarboxylic Acid is a high-purity chiral intermediate of significant importance in advanced organic synthesis. This compound matters because it serves as a critical building block for the development of novel pharmaceuticals, particularly in the creation of enantiomerically pure active pharmaceutical ingredients (APIs). Industries that need it include pharmaceutical R&D, fine chemical manufacturing, and academic research institutions focused on medicinal chemistry and asymmetric synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug molecules, particularly those targeting neurological and cardiovascular pathways.
• Asymmetric Catalyst Research: Used as a precursor or ligand in the development of novel chiral catalysts for stereoselective reactions.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and the design of new chemical entities with potential therapeutic activity.
• Fine Chemical Synthesis: Serves as a versatile starting material for the preparation of other specialized quinoline derivatives and heterocyclic compounds.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	(S)-1,2,3,4-Tetrahydro-4-Oxo-2-Quinolinecarboxylic Acid
CAS No.	492-26-2
Molecular Formula	C10H9NO3
Molecular Weight	191.18 g/mol
Synonyms	(S)-1,2,3,4-Tetrahydro-4-oxoquinoline-2-carboxylic acid; (S)-2-Carboxy-1,2,3,4-tetrahydro-4-oxoquinoline; (S)-4-Oxo-1,2,3,4-tetrahydroquinoline-2-carboxylic acid; L-1,2,3,4-Tetrahydro-4-oxo-2-quinolinecarboxylic acid; (S)-TQCA; (S)-THQCA; (S)-2-Quinolinecarboxylic acid, 1,2,3,4-tetrahydro-4-oxo-; (S)-4-Oxo-1,2,3,4-tetrahydro-2-quinolinecarboxylic acid
EINECS	207-764-6

Quality Control

Our (S)-1,2,3,4-Tetrahydro-4-Oxo-2-Quinolinecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.