Description

1,2-Bisn-Cytisinylethane is a specialized alkaloid derivative of cytisine, a compound of significant interest in pharmacological research. This product matters as a high-purity chemical intermediate, enabling the synthesis and study of novel nicotinic acetylcholine receptor (nAChR) ligands. It is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers focused on developing new therapeutic agents for neurological conditions and smoking cessation aids.

Application

• Pharmaceutical Research Intermediate: A key building block in the synthesis of novel compounds targeting nicotinic acetylcholine receptors (nAChRs).
• Neuroscience Studies: Used in preclinical research to investigate receptor binding, function, and modulation for potential cognitive or neurological therapies.
• Lead Compound Development: Serves as a structural scaffold for medicinal chemists to develop new drug candidates with optimized efficacy and selectivity.
• Reference Standard: Employed as an analytical standard in HPLC, LC-MS, or NMR for quality control and method validation in related research.
• Biochemical Tool Compound: Utilized in in vitro assays to study receptor-ligand interactions and signal transduction pathways.

Basic Information

Product Name	1,2-Bisn-Cytisinylethane
CAS No.	492-02-4
Molecular Formula	C₂₂H₃₀N₄O₂
Molecular Weight	382.50 g/mol
Synonyms	1,2-Bis(cytisin-12-yl)ethane; N,N'-Ethane-1,2-diylbiscytisine; Cytisine dimer; 1,2-Di(cytisin-12-yl)ethane; Bis-cytisine ethane; Labdane dimer derivative; (1R,2R,5S,9S,10S,13S)-2,13-Dimethyl-15-oxapentacyclo[12.2.1.0¹,¹⁰.0²,⁹.0⁵,⁸]heptadec-7-en-6-one dimer
EINECS	Contact for details

Quality Control

Our 1,2-Bisn-Cytisinylethane is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles for research-grade chemicals, and specifications can be aligned with client requirements for advanced pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.