Description

[(3R,7R)-7-Hydroxy-8-Methyl-8-Azabicyclo[3.2.1]Oct-3-Yl] 3-Methylbutan Oate is a high-purity, stereochemically defined tropane alkaloid derivative. This compound is of significant interest for its role as a key synthetic intermediate and reference standard in advanced pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A crucial chiral building block for the synthesis of novel tropane-based pharmaceuticals, including potential central nervous system (CNS) agents and anticholinergic drugs.
• Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control in regulatory filings.
• Asymmetric Synthesis: Employed in stereoselective synthesis due to its defined (3R,7R) configuration, enabling the construction of complex molecular architectures.
• Medicinal Chemistry Research: Serves as a scaffold or precursor for structure-activity relationship (SAR) studies in drug discovery programs.
• Process Chemistry: Utilized in the development and scale-up of synthetic routes for active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Acts as an intermediate in the research and production of specialized agrochemicals with specific biological activity.

Basic Information

Product Name	[(3R,7R)-7-Hydroxy-8-Methyl-8-Azabicyclo[3.2.1]Oct-3-Yl] 3-Methylbutan Oate
CAS No.	490-96-0
Molecular Formula	C14H25NO3
Molecular Weight	255.36 g/mol
Synonyms	3β-Tropanyl isovalerate; 3-Tropanyl isovalerate; Tropan-3β-ol, 8-methyl-, 3-isovalerate; (1R,3r,5S)-8-Methyl-8-azabicyclo[3.2.1]octan-3-yl 3-methylbutanoate; 3β-Hydroxytropane isovalerate; Pseudotropine isovalerate; Isovaleric acid tropan-3β-yl ester
EINECS	207-722-3

Quality Control

Our [(3R,7R)-7-Hydroxy-8-Methyl-8-Azabicyclo[3.2.1]Oct-3-Yl] 3-Methylbutan Oate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, identity, and purity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% (3R,7R)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.