Description

Propyphenazone is a synthetic organic compound belonging to the pyrazolone class, widely recognized for its analgesic and antipyretic properties. This high-purity active pharmaceutical ingredient (API) is essential for ensuring the efficacy and safety of finished pharmaceutical formulations. It is primarily utilized by pharmaceutical manufacturers and research institutions in the development and production of analgesic and fever-reducing medications.

Application

• Pharmaceutical API: Primary use as the active ingredient in analgesic and antipyretic drug formulations.
• Combination Drug Products: Used in fixed-dose combination medications with other APIs for enhanced therapeutic effects.
• Analgesic Research: Serves as a key reference standard and intermediate in pharmacological research for pain management.
• Veterinary Medicine: Employed in the formulation of analgesic treatments for animals.
• Chemical Synthesis: Acts as a crucial intermediate or starting material for the synthesis of more complex pharmaceutical compounds.

Basic Information

Product Name	Propyphenazone
CAS No.	479-92-5
Molecular Formula	C14H18N2O
Molecular Weight	230.31 g/mol
Synonyms	Isopropylphenazone; 4-Isopropyl-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one; 1-Phenyl-2,3-dimethyl-4-isopropyl-5-pyrazolone; Propyphenazon; Isopropylantipyrine; Isopropylphenazon; Noramidopyrine methanesulfonate sodium (related salt); Contact for details on additional trade names.
EINECS	207-538-1

Quality Control

Our Propyphenazone is manufactured under strict quality management systems to meet the rigorous standards of the pharmaceutical industry. Each batch is subjected to comprehensive analytical testing, including identification, assay, and impurity profiling, to ensure compliance with pharmacopeial specifications such as USP/EP. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light exposure to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on dried basis)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.