Description

Hamamelitannin is a hydrolyzable tannin, specifically a gallotannin, naturally derived from the bark and leaves of the witch hazel plant (*Hamamelis virginiana*). This compound is valued for its potent antioxidant and anti-inflammatory properties, making it a key bioactive ingredient in advanced formulations. It is primarily sought by manufacturers in the cosmetic, personal care, pharmaceutical, and nutraceutical industries for developing high-performance skincare, therapeutic, and wellness products.

Application

• Cosmetic & Skincare Formulations: Used as a stabilizing and active ingredient in anti-aging serums, creams, and lotions for its antioxidant and skin-soothing effects.
• Pharmaceutical Research: Investigated for its potential therapeutic applications, including anti-inflammatory, antiviral, and chemopreventive agents.
• Nutraceuticals & Dietary Supplements: Incorporated into supplements targeting oxidative stress and inflammation management.
• Topical Preparations: A key component in aftershaves, toners, and ointments designed to calm irritation and reduce redness.
• Natural Preservative Systems: Explored for its ability to enhance the stability and shelf-life of natural product formulations.
• Hair Care Products: Used in shampoos and scalp treatments to promote scalp health and reduce irritation.

Basic Information

Product Name	Hamamelitannin
CAS No.	469-32-9
Molecular Formula	C27H22O18
Molecular Weight	634.45 g/mol
Synonyms	1,2,3,4,6-Penta-O-galloyl-β-D-glucose; 2,3,4,6-Tetrakis-O-galloyl-D-glucose 1-O-gallate; Hamamelis Tannin; Witch Hazel Tannin; Gallotannin; Tannic acid component; PGG
EINECS	207-419-1

Quality Control

Our Hamamelitannin is produced and tested under strict quality management protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing key parameters such as assay, identity, and impurity profiles. Our quality systems are designed to support applications requiring traceability and reliability, from cosmetic R&D to pharmaceutical-grade research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity for oxidation, prolonged exposure to light, heat, or air should be avoided to maintain stability and potency.

Specification

Item	Specification
Appearance	Light yellow to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Loss on Drying	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals (as Pb)	≤ 20 ppm
Total Microbial Count	≤ 1000 CFU/g
Yeast & Mold	≤ 100 CFU/g

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.