Description

(1R,9Aα)-Octahydro-4β-(3-Furyl)-1,7β-Dimethyl-2H-Quinolizine 5α-Oxide is a complex, stereochemically defined alkaloid derivative with significant potential as a key chiral intermediate in advanced organic synthesis. Its unique fused quinolizine-oxazine structure makes it a valuable scaffold for pharmaceutical research and development, particularly in the creation of novel bioactive molecules. This compound is primarily sought by research institutions and fine chemical manufacturers specializing in the synthesis of complex natural products, pharmaceutical candidates, and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block for the synthesis of potential drug candidates targeting neurological and other therapeutic areas.
• Asymmetric Synthesis: Used as a starting material or intermediate in catalytic and stoichiometric asymmetric reactions due to its defined stereocenters.
• Natural Product Synthesis: Acts as a key intermediate in the total or semi-synthesis of complex alkaloids and other natural products.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and library synthesis for hit-to-lead optimization.
• Chemical Reference Standard: Used as a high-purity analytical standard for method development and quality control in research and development.
• Specialty Fine Chemicals: Incorporated into the synthesis of advanced materials, ligands for catalysis, or other high-value, low-volume chemical products.

Basic Information

Item	Detail
Product Name	(1R,9Aα)-Octahydro-4β-(3-Furyl)-1,7β-Dimethyl-2H-Quinolizine 5α-Oxide
CAS No.	468-89-3
Molecular Formula	C15H23NO2
Molecular Weight	249.35 g/mol
Synonyms	4β-(3-Furyl)-1,7β-dimethyloctahydro-2H-quinolizine 5α-oxide; (1R,9aα)-Octahydro-4β-(3-furyl)-1,7β-dimethyl-2H-quinolizine 5α-oxide; 1,7β-Dimethyl-4β-(3-furyl)octahydro-2H-quinolizine 5α-oxide; 4β-(3-Furyl)-1,7β-dimethyloctahydro-2H-quinolizine 5α-oxide; Furan-containing quinolizidine N-oxide; 468-89-3; Quinolizine oxide derivative
EINECS	Contact for details

Quality Control

Our (1R,9Aα)-Octahydro-4β-(3-Furyl)-1,7β-Dimethyl-2H-Quinolizine 5α-Oxide is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring compliance with research-grade specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 98.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.