Description

Colupulone is a key beta acid component found in hops (Humulus lupulus), characterized by its specific prenylated phloroglucinol structure. This compound is of significant commercial interest due to its role as a precursor in the isomerization process that produces iso-alpha acids, which are critical for beer bitterness and flavor stability. It is primarily utilized by manufacturers in the brewing industry and suppliers of hop extracts for the production of consistent, high-quality beer. Researchers also value this material for studying hop chemistry and developing new brewing products.

Application

• Brewing Industry: Serves as a direct precursor for the production of iso-alpha acids, the primary bittering compounds in beer.
• Hop Extract Production: Used in the formulation of standardized hop extracts and advanced hop products for consistent bittering potential.
• Flavor and Bitterness Profiling: Essential for research and development aimed at controlling and modifying the bitterness profile of finished beers.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for HPLC and other chromatographic methods to quantify hop acids.
• Chemical Synthesis: Acts as a starting material or intermediate for the synthesis of specialized hop-derived compounds and analogues.
• Research & Development: Utilized in academic and industrial research to study the properties, stability, and transformations of hop beta acids.

Basic Information

Product Name	Colupulone
CAS No.	468-27-9
Molecular Formula	C26H38O4
Molecular Weight	414.58 g/mol
Synonyms	Colupulone; β-Colupulone; 3,5-Dihydroxy-2-(3-methylbut-2-en-1-yl)-4,6-bis(3-methylbutanoyl)benzene; 4,6-Di(3-methylbutyryl)-2-(3-methyl-2-butenyl)-1,3,5-benzenetriol; Hop beta acid; β-Acid (Colupulone); Lupulone, co-; NSC 407296
EINECS	Contact for details

Quality Control

Our Colupulone is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques like HPLC to confirm identity and assay. A comprehensive Certificate of Analysis (COA) detailing purity, related substances, and other critical parameters is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at controlled room temperature (15-25°C) to minimize oxidation and degradation. Keep the container sealed when not in use to prevent moisture absorption.

Specification

Item	Specification
Appearance	Yellow to pale brown powder or resin
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Loss on Drying	≤ 2.0 %
Residue on Ignition	≤ 0.5 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.