Description

4-Hydroxyphenyl Trifluoromethyl Sulphone is a high-value, multi-functional aromatic sulfone derivative characterized by its trifluoromethyl and phenolic hydroxyl groups. This unique structure makes it a versatile and critical pharmaceutical intermediate and advanced chemical building block for synthesizing complex organic molecules. It is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and enzyme inhibitors.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and pesticides with enhanced efficacy and environmental profiles.
• Liquid Crystal Materials: Used in the production of high-performance liquid crystal displays (LCDs) due to its stable aromatic core and polar substituents.
• Polymer Modification: Serves as a monomer or additive to impart specific properties like thermal stability, chemical resistance, or low surface energy to advanced polymers.
• Organic Synthesis Reagent: Utilized in cross-coupling reactions, nucleophilic substitutions, and as a directing group in complex multi-step organic syntheses in R&D laboratories.
• Material Science Research: Investigated for use in organic semiconductors, photovoltaic materials, and other electronic applications.

Basic Information

Product Name	4-Hydroxyphenyl Trifluoromethyl Sulphone
CAS No.	432-84-8
Molecular Formula	C7H5F3O3S
Molecular Weight	226.17 g/mol
Synonyms	1-Hydroxy-4-(trifluoromethylsulfonyl)benzene; p-(Trifluoromethylsulfonyl)phenol; 4-(Trifluoromethanesulfonyl)phenol; 4-Hydroxybenzenesulfonic acid trifluoromethyl ester; Trifluoromethyl 4-hydroxyphenyl sulfone; 4-Trifluoromethanesulfonylphenol; Phenol, 4-[(trifluoromethyl)sulfonyl]-
EINECS	207-093-3

Quality Control

Our 4-Hydroxyphenyl Trifluoromethyl Sulphone is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure high purity and consistent performance. We provide detailed Certificates of Analysis (COA) with each shipment, documenting key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. Due to its phenolic nature, standard laboratory safety practices for handling fine chemicals should be observed.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.