Description

(Trifluoromethyl)Dichlorophosphine is a highly reactive organophosphorus compound characterized by a phosphorus atom bonded to a trifluoromethyl group and two chlorine atoms. This unique structure makes it a valuable and versatile building block for synthesizing complex fluorinated phosphorus ligands and advanced materials. It is primarily sought after by research chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for introducing the (trifluoromethyl)phosphine moiety into target molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel fluorinated phosphine ligands used in asymmetric catalysis for chiral drug manufacturing.
• Agrochemical Synthesis: Building block for creating advanced fluorinated organophosphorus active ingredients and ligands with enhanced biological activity and environmental stability.
• Ligand Precursor: Serves as a starting material for the preparation of specialized phosphine ligands critical in transition metal catalysis for fine chemical production.
• Material Science Research: Used in the development of fluorinated phosphorus-containing polymers, flame retardants, and electronic materials.
• Organic Synthesis Reagent: Employed in laboratories for the introduction of the -P(CF3)Cl2 or derived functional groups into organic frameworks.
• Catalyst Development: Intermediate in the creation of metal-phosphine complexes for catalytic processes like hydrogenation and cross-coupling reactions.

Basic Information

Product Name	(Trifluoromethyl)Dichlorophosphine
CAS No.	421-58-9
Molecular Formula	CCl2F3P
Molecular Weight	168.88 g/mol
Synonyms	Dichloro(trifluoromethyl)phosphine; Trifluoromethyldichlorophosphine; (Trifluoromethyl)phosphonous Dichloride; Phosphonous dichloride, P-(trifluoromethyl)-; CF3PCl2; P-(Trifluoromethyl)phosphonous dichloride
EINECS	207-020-7

Quality Control

Our (Trifluoromethyl)Dichlorophosphine is produced and handled under strict quality management protocols. Each batch undergoes rigorous analytical testing, including GC and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your research and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area, preferably under an inert atmosphere such as nitrogen or argon due to its moisture-sensitive and highly volatile nature. Keep away from heat, sparks, and open flame. Incompatible with strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.