Description

Trifluoromethylphosphane is a highly reactive organophosphorus compound containing a phosphorus-carbon bond and three fluorine atoms. This unique structure makes it a valuable specialty reagent and building block in advanced chemical synthesis. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and materials science sectors for the development of novel compounds and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring fluorinated or phosphorus-containing motifs.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the trifluoromethylphosphane group can enhance biological activity and stability.
• Ligand in Catalysis: Acts as a precursor for the preparation of specialized phosphine ligands used in transition metal catalysis for fine chemical production.
• Materials Science Research: Employed in the development of novel polymers, flame retardants, and electronic materials due to its reactive P-C bond and fluorine content.
• Organofluorine Chemistry: A versatile building block for introducing the -CF3P moiety into complex organic molecules, expanding the toolbox for fluorination strategies.

Basic Information

Product Name	Trifluoromethylphosphane
CAS No.	420-52-0
Molecular Formula	CF3PH2
Molecular Weight	102.00 g/mol
Synonyms	Trifluoromethylphosphine; (Trifluoromethyl)phosphine; Phosphino(trifluoromethane); Trifluoromethanephosphine; Methylphosphine, trifluoro-; CF3PH2; Trifluoromethylphosphane; Trifluoromethylphosphine (PH2 derivative)
EINECS	206-997-2

Quality Control

Our Trifluoromethylphosphane is produced and handled under strict quality protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analysis, including GC, NMR, and titration methods, to verify identity and assay. A detailed Certificate of Analysis (COA) documenting purity and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile and reactive nature, this material should be stored under an inert atmosphere (e.g., nitrogen or argon) at temperatures between 2°C and 8°C. Keep the container in a cool, well-ventilated place, away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless gas / liquefied gas
Identification (IR)	Conforms to reference spectrum
Assay (GC)	≥ 98.0%
Purity (NMR)	Conforms
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.