Description

Urea, N,N'-Bis(2,2,2-Trifluoroethyl)- is a specialized fluorinated urea derivative, distinguished by its two trifluoroethyl substituents. This molecular structure imparts unique properties, making it a valuable building block and intermediate in advanced chemical synthesis. It is primarily utilized in the research and development of pharmaceuticals, agrochemicals, and high-performance materials. Its targeted applications appeal to industries requiring precise fluorination to modify compound characteristics such as lipophilicity, metabolic stability, and biological activity.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs for enhanced bioavailability and target binding.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and pesticides where the trifluoroethyl group can influence potency and environmental persistence.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialty polymers and coatings with potential for improved chemical resistance and surface properties.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex molecules, leveraging the urea functionality for hydrogen bonding and the fluorine atoms for electronic effects.
• Ligand and Catalyst Development: Investigated for use in designing novel ligands for metal catalysis or as a component in organocatalysis due to its unique electronic profile.

Basic Information

Product Name	Urea, N,N'-Bis(2,2,2-Trifluoroethyl)-
CAS No.	406-11-1
Molecular Formula	C5H6F6N2O
Molecular Weight	224.11 g/mol
Synonyms	1,1'-(Carbonylbis(azanediyl))bis(2,2,2-trifluoroethane); N,N'-Bis(2,2,2-trifluoroethyl)urea; 1,3-Bis(2,2,2-trifluoroethyl)urea; Bis(2,2,2-trifluoroethyl)urea; Urea, 1,3-bis(2,2,2-trifluoroethyl)-; Trifluoroethyl Urea Derivative
EINECS	Contact for details

Quality Control

Our Urea, N,N'-Bis(2,2,2-Trifluoroethyl)- is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay, impurity profile, and physical characteristics are provided and available upon request, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from strong bases and strong oxidizing agents. For long-term storage, consider conditions under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.