Description

4-(2-Bromoethyl)-2-Fluoro-1-Methoxybenzene is a versatile fluorinated aromatic building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring both a reactive bromoethyl side chain and a fluorine substituent, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used to introduce fluorinated aromatic motifs into novel herbicides, fungicides, and pesticides to enhance their biological activity and stability.
• Liquid Crystal & OLED Material Development: Serves as a building block for fluorinated components in electronic display and lighting materials.
• Cross-Coupling Reactions: The bromoethyl moiety acts as an electrophile in Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds.
• Functional Polymer Modification: Used to incorporate fluorine and reactive sites into polymer backbones for specialized material properties.
• Chemical Research & Process Development: A valuable reagent for method development and scaling in process chemistry for fine chemical production.

Basic Information

Product Name	4-(2-Bromoethyl)-2-Fluoro-1-Methoxybenzene
CAS No.	404-89-7
Molecular Formula	C9H10BrFO
Molecular Weight	233.08 g/mol
Synonyms	2-Fluoro-4-(2-bromoethyl)anisole; 1-Bromo-2-(2-fluoro-4-methoxyphenyl)ethane; 2-(2-Fluoro-4-methoxyphenyl)ethyl bromide; 4-(2-Bromoethyl)-2-fluoroanisole; (2-Fluoro-4-methoxyphenyl)ethyl bromide; 2-Bromo-1-(2-fluoro-4-methoxyphenyl)ethane; 404-89-7; 2-Fluoro-4-(2-bromoethyl)methoxybenzene
EINECS	Contact for details

Quality Control

Our 4-(2-Bromoethyl)-2-Fluoro-1-Methoxybenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.