Description

n-(4-Chlorophenyl)-2-Fluoroacetamide is a high-purity fluorinated acetamide derivative, serving as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular structure, which incorporates both chloro and fluoro substituents to modulate reactivity and physicochemical properties in target molecules. It is primarily utilized by research institutions and industrial R&D departments engaged in the development of novel agrochemicals, pharmaceuticals, and specialty materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a fluorinated aromatic moiety for enhanced metabolic stability and bioavailability.
• Agrochemical Research: Serves as a versatile scaffold for developing new herbicides, fungicides, and insecticides, where the chlorophenyl and fluoroacetamide groups contribute to target specificity.
• Organic Synthesis Building Block: Used in cross-coupling reactions, amide bond formations, and as a starting material for heterocyclic compounds in academic and industrial research laboratories.
• Material Science: Potential monomer or additive in the research of specialty polymers and liquid crystals, leveraging its aromatic and polar functional groups.
• Biochemical Probe Development: Employed in medicinal chemistry for structure-activity relationship (SAR) studies to investigate protein-ligand interactions.

Basic Information

Item	Detail
Product Name	n-(4-Chlorophenyl)-2-Fluoroacetamide
CAS No.	404-41-1
Molecular Formula	C8H7ClFNO
Molecular Weight	187.60 g/mol
Synonyms	2-Fluoro-N-(4-chlorophenyl)acetamide; 4'-Chloro-2-fluoroacetanilide; N-(p-Chlorophenyl)-2-fluoroacetamide; p-Chloro-2-fluoroacetanilide; 2-Fluoroacet-4'-chloroanilide; 404-41-1; N-(4-Chlorophenyl)-2-fluoroacetamide
EINECS	Contact for details

Quality Control

Every batch of n-(4-Chlorophenyl)-2-Fluoroacetamide is manufactured under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.