Description

1,2-Dichloro-5-Nitro-3-(Trifluoromethyl)Benzene is a versatile halogenated nitrobenzene derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring chlorine, nitro, and trifluoromethyl substituents, makes it a valuable intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by R&D chemists and process development teams in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring halogenated or fluorinated aromatic cores for enhanced bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group often contributes to improved efficacy and environmental profile.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Intermediate: Employed in the synthesis of complex, high-performance dyes and pigments due to its electron-withdrawing substituents.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to construct biaryl systems for various applications.

Basic Information

Product Name	1,2-Dichloro-5-Nitro-3-(Trifluoromethyl)Benzene
CAS No.	400-65-7
Molecular Formula	C7H2Cl2F3NO2
Molecular Weight	260.00 g/mol
Synonyms	2,3-Dichloro-6-nitrobenzotrifluoride; 3,4-Dichloro-2-nitrobenzotrifluoride; 1,2-Dichloro-5-nitro-α,α,α-trifluorotoluene; 2,3-Dichloro-α,α,α-trifluoro-6-nitrotoluene; Benzene, 1,2-dichloro-5-nitro-3-(trifluoromethyl)-; 3-(Trifluoromethyl)-1,2-dichloro-5-nitrobenzene; 2-Nitro-3,4-dichlorobenzotrifluoride
EINECS	Contact for details

Quality Control

Our 1,2-Dichloro-5-Nitro-3-(Trifluoromethyl)Benzene is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.