Description

Oxirane, 2-Cyclohexyl-3-Ethynyl-, (2R,3S)-Rel- (9Ci) is a chiral, functionalized oxirane (epoxide) building block of significant interest in advanced organic synthesis. Its unique structure, featuring both a cyclohexyl and an ethynyl substituent on a stereodefined oxirane ring, makes it a valuable precursor for constructing complex, three-dimensional molecular architectures. This high-purity intermediate is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and chiral ligands.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of novel, stereospecific pesticides and herbicides where the defined spatial orientation of the molecule is critical for biological activity.
• Asymmetric Catalysis: Serves as a precursor for the development of new chiral catalysts and ligands used in enantioselective synthesis.
• Advanced Material Research: Employed in the synthesis of specialized polymers and resins with tailored thermal or mechanical properties, leveraging its reactive epoxide and alkyne functionalities.
• Academic & Contract Research: A valuable tool for methodology development and total synthesis projects in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	Oxirane, 2-Cyclohexyl-3-Ethynyl-, (2R,3S)-Rel- (9Ci)
CAS No.	399512-82-4
Molecular Formula	C10H14O
Molecular Weight	150.22 g/mol
Synonyms	(2R,3S)-2-Cyclohexyl-3-ethynyloxirane; rel-(2R,3S)-2-Cyclohexyl-3-ethynyloxirane; 2-Cyclohexyl-3-ethynyloxirane, (2R,3S)-rel-; Chiral Cyclohexyl Ethynyl Oxirane; (2R,3S)-rel-2-Cyclohexyl-3-ethynyl-oxirane; 399512-82-4; (2R,3S)-2-Cyclohexyl-3-ethynyl-oxirane
EINECS	Contact for details

Quality Control

Our production of Oxirane, 2-Cyclohexyl-3-Ethynyl-, (2R,3S)-Rel- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity suitable for research and development applications. Each lot undergoes comprehensive analytical characterization, including chiral purity assessment. A Certificate of Analysis (COA) detailing identity, purity (by GC/HPLC), enantiomeric excess, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.