Description

1H-Benzimidazole,1-Methyl-6-(Trifluoromethyl)-(9Ci) is a high-purity, trifluoromethyl-substituted benzimidazole derivative, a privileged scaffold in modern organic synthesis. This compound matters for its role as a key synthetic intermediate, offering a versatile chemical handle for constructing complex molecules with tailored properties. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for drug discovery and advanced material science applications.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and antiviral agents.
• Agrochemical Research: Used in the discovery and development of new fungicides and herbicides, leveraging the bioactivity of the benzimidazole core.
• Material Science: Serves as a precursor for advanced organic materials, including ligands for catalysis and components for organic light-emitting diodes (OLEDs).
• Chemical Synthesis: Acts as a versatile synthon in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Academic & Contract Research: Employed in university and CRO laboratories for fundamental research in heterocyclic chemistry and fluorine chemistry.

Basic Information

Product Name	1H-Benzimidazole,1-Methyl-6-(Trifluoromethyl)-(9Ci)
CAS No.	397869-98-6
Molecular Formula	C9H7F3N2
Molecular Weight	200.16 g/mol
Synonyms	1-Methyl-6-(trifluoromethyl)-1H-benzimidazole; 6-(Trifluoromethyl)-1-methyl-1H-benzimidazole; 1-Methyl-6-trifluoromethylbenzimidazole; 1-Methyl-6-(trifluoromethyl)benzimidazole; Benzimidazole, 1-methyl-6-(trifluoromethyl)-; 397869-98-6
EINECS	Contact for details

Quality Control

Our 1H-Benzimidazole,1-Methyl-6-(Trifluoromethyl)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from moisture and direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.