Description

1,8-Naphthyridine-3-Carboxylicacid,4-Hydroxy-5-Methyl-,Ethylester(9Ci) is a high-purity, synthetically valuable naphthyridine derivative. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in organic synthesis. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for developing novel active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting bacterial or viral infections.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its bioactive heterocyclic core.
• Ligand Synthesis: Serves as a starting material for creating chelating ligands in coordination chemistry and catalysis.
• Fluorescent Probe Development: Utilized in material science and bioimaging for constructing naphthyridine-based fluorescent markers.
• Organic Synthesis Building Block: Employed in multi-step synthetic routes to construct more complex polycyclic or functionalized heterocyclic systems.
• Academic & Industrial R&D: Essential for medicinal chemistry programs and process development in contract research and manufacturing organizations (CROs/CMOs).

Basic Information

Product Name	1,8-Naphthyridine-3-Carboxylicacid,4-Hydroxy-5-Methyl-,Ethylester(9Ci)
CAS No.	397845-42-0
Molecular Formula	C₁₂H₁₂N₂O₃
Molecular Weight	232.24 g/mol
Synonyms	4-Hydroxy-5-methyl-1,8-naphthyridine-3-carboxylic acid ethyl ester; Ethyl 4-hydroxy-5-methyl-1,8-naphthyridine-3-carboxylate; 5-Methyl-4-hydroxy-1,8-naphthyridine-3-carboxylic acid ethyl ester; 1,8-Naphthyridine-3-carboxylic acid, 4-hydroxy-5-methyl-, ethyl ester; 397845-42-0; Ethyl 5-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate
EINECS	Contact for details

Quality Control

Our 1,8-Naphthyridine-3-Carboxylicacid,4-Hydroxy-5-Methyl-,Ethylester(9Ci) is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.