Description

Oxazole, 4,5-Dihydro-2-[2-[(R)-(4-Methylphenyl)Sulfinyl]Phenyl]-4-Phenyl-, (4S)- is a high-purity, chiral oxazole derivative characterized by its sulfinyl group and defined stereochemistry at the (4S) position. This compound is a critical advanced pharmaceutical intermediate (API) used in the synthesis of complex, biologically active molecules. It is primarily required by pharmaceutical R&D and fine chemical synthesis teams for developing new therapeutic agents, particularly in areas requiring precise stereochemical control.

Application

• Pharmaceutical Intermediate: A key chiral building block in the research and development of new active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and anti-inflammatory targets.
• Asymmetric Synthesis: Utilized as a ligand or precursor in catalytic asymmetric reactions to induce chirality in target molecules.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and the creation of novel compound libraries for high-throughput screening.
• Process Chemistry Development: Used in scaling up synthetic routes from laboratory to pilot plant scale for potential commercial drug manufacturing.
• Academic & Institutional Research: Employed in universities and research institutes for studies in organic synthesis, heterocyclic chemistry, and drug discovery methodologies.

Basic Information

Item	Detail
Product Name	Oxazole, 4,5-Dihydro-2-[2-[(R)-(4-Methylphenyl)Sulfinyl]Phenyl]-4-Phenyl-, (4S)-
CAS No.	396094-85-2
Molecular Formula	C22H19NO2S
Molecular Weight	361.46 g/mol
Synonyms	(4S)-4,5-Dihydro-2-[2-[(R)-(4-Methylphenyl)sulfinyl]phenyl]-4-phenyloxazole; (S)-2-(2-((R)-(p-Tolyl)sulfinyl)phenyl)-4-phenyl-4,5-dihydrooxazole; Chiral Oxazole Sulfoxide; (S)-4-Phenyl-2-(2-((R)-(p-tolylsulfinyl))phenyl)-4,5-dihydrooxazole; 4,5-Dihydro-2-[2-[(R)-(4-methylphenyl)sulfinyl]phenyl]-4-phenyl-, (4S)-Oxazole; p-Tolylsulfinylphenyl Dihydrooxazole Derivative; Advanced Chiral Oxazole Intermediate
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to strict quality management systems. Every batch is analyzed using advanced chromatographic (HPLC, GC) and spectroscopic (NMR, IR) techniques to confirm identity, chiral purity (enantiomeric excess), and chemical purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to ensure traceability and compliance with your research or production protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. The container must be kept tightly sealed to protect the product from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% e.e.
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.