Description

6-Fluoro-4,4-Dimethyl-1,3-Dihydroquinolin-2-One is a high-value, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core quinolinone scaffold, strategically substituted with fluorine and gem-dimethyl groups, makes it a critical intermediate for developing novel bioactive molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and anti-infective targets.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the fluorine atom.
• Material Science: Acts as a building block for specialty polymers and advanced organic electronic materials due to its rigid, fused-ring structure.
• Chemical Synthesis: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis to explore new chemical space.
• Fluorine Chemistry: A valuable substrate for further fluorination or functionalization reactions, capitalizing on the existing fluorine handle.

Basic Information

Product Name	6-Fluoro-4,4-Dimethyl-1,3-Dihydroquinolin-2-One
CAS No.	395673-46-8
Molecular Formula	C₁₁H₁₀FNO
Molecular Weight	191.20 g/mol
Synonyms	6-Fluoro-4,4-dimethyl-1,2-dihydroquinolin-2-one; 6-Fluoro-4,4-dimethyl-2-oxo-1,2-dihydroquinoline; 4,4-Dimethyl-6-fluoro-1,2-dihydroquinolin-2-one; 6-Fluoro-4,4-dimethyl-2(1H)-quinolinone; 6-Fluoro-4,4-dimethylquinolin-2(1H)-one; 395673-46-8; 6-Fluoro-4,4-dimethyl-1H-quinolin-2-one
EINECS	Contact for details

Quality Control

Our 6-Fluoro-4,4-Dimethyl-1,3-Dihydroquinolin-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide Certificates of Analysis (COA) with every shipment, detailing all specifications and test results to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.