Description

1H-Indole-2-Carboxylic Acid, 4,7-Difluoro-, Ethyl Ester is a high-value fluorinated indole derivative, a crucial building block in advanced organic synthesis. Its core value lies in its role as a versatile intermediate for constructing complex molecules with tailored biological and material properties. This compound is primarily needed by research and development teams in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in oncology, neurology, and anti-inflammatory research.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms enhance biological activity and stability.
• Material Science Research: Serves as a precursor for organic electronic materials, such as OLEDs and semiconductors, due to the indole core's electronic properties.
• Chemical Biology Probes: Employed in the synthesis of fluorescent tags and molecular probes for studying biological processes.
• Academic & Contract Research: Essential for methodological development and exploratory synthesis in university and CRO laboratories.
• Fine Chemical Production: Acts as a building block for the custom synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	1H-Indole-2-Carboxylic Acid, 4,7-Difluoro-, Ethyl Ester
CAS No.	394223-44-0
Molecular Formula	C11H9F2NO2
Molecular Weight	225.19 g/mol
Synonyms	4,7-Difluoro-1H-indole-2-carboxylic acid ethyl ester; Ethyl 4,7-difluoro-1H-indole-2-carboxylate; 4,7-Difluoroindole-2-carboxylic Acid Ethyl Ester; 1H-Indole-2-carboxylic acid, 4,7-difluoro-, ethyl ester; 394223-44-0; Ethyl 4,7-difluoroindole-2-carboxylate; 4,7-Difluoro-2-indolecarboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 1H-Indole-2-Carboxylic Acid, 4,7-Difluoro-, Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to quality supports applications requiring high-purity intermediates for research and cGMP-compliant synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storage under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.