Description

1-(2,4-Dimethylphenyl)-4-(3-Methylpiperidin-1-Yl)-1H-Pyrazolo[3,4-D]Pyrimidine CAS NO 393845-24-4 is a high-purity, advanced pharmaceutical intermediate belonging to the pyrazolopyrimidine class of heterocyclic compounds. This compound is valued for its role as a critical building block in the synthesis of targeted therapeutic agents, particularly kinase inhibitors. It is essential for research institutions and pharmaceutical manufacturers engaged in the development of novel small-molecule drugs for oncology and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potent kinase inhibitor candidates for cancer therapy.
• Biochemical Research: Used as a reference standard or a core scaffold in medicinal chemistry programs for structure-activity relationship (SAR) studies.
• Drug Discovery & Development: Serves as a vital building block for constructing novel chemical entities (NCEs) in high-throughput screening libraries.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the cGMP production of active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for investigating new synthetic pathways and biological mechanisms.

Basic Information

Product Name	1-(2,4-Dimethylphenyl)-4-(3-Methylpiperidin-1-Yl)-1H-Pyrazolo[3,4-D]Pyrimidine
CAS No.	393845-24-4
Molecular Formula	C19H23N5
Molecular Weight	321.42 g/mol
Synonyms	1-(2,4-Dimethylphenyl)-4-(3-methyl-1-piperidinyl)-1H-pyrazolo[3,4-d]pyrimidine; 4-(3-Methylpiperidin-1-yl)-1-(2,4-dimethylphenyl)-1H-pyrazolo[3,4-d]pyrimidine; UNII-1Q6KQ8Q8F2; 1Q6KQ8Q8F2; Pyrazolo[3,4-d]pyrimidine, 1-(2,4-dimethylphenyl)-4-(3-methyl-1-piperidinyl)-; SCHEMBL2180207; BDBM50389335; AKOS025147310
EINECS	Contact for details

Quality Control

Our 1-(2,4-Dimethylphenyl)-4-(3-Methylpiperidin-1-Yl)-1H-Pyrazolo[3,4-D]Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic data are provided to support research and cGMP compliance. We adhere to ICH guidelines for stability and impurity profiling.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.