Description

1,8-Naphthyridine-3-Carboxamide,n-[4-(1-Methylethoxy)Phenyl]-2-(Trifluoromethyl)-(9Ci) is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure incorporating a trifluoromethyl group. This compound is of significant value in modern medicinal chemistry for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly in areas requiring sophisticated molecular scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, especially those targeting complex disease pathways.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging the biological activity of the naphthyridine core.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex heterocyclic molecules for material science or catalysis.
• Fluorinated Compound Synthesis: The presence of the trifluoromethyl group makes it a valuable reagent for introducing fluorine into target molecules to modulate their physicochemical properties.
• Ligand Development: Potential use in creating specialized ligands for metal-organic frameworks (MOFs) or catalytic systems.

Basic Information

Product Name	1,8-Naphthyridine-3-Carboxamide,n-[4-(1-Methylethoxy)Phenyl]-2-(Trifluoromethyl)-(9Ci)
CAS No.	393183-72-7
Molecular Formula	C19H16F3N3O2
Molecular Weight	375.35 g/mol
Synonyms	N-[4-(1-Methylethoxy)phenyl]-2-(trifluoromethyl)-1,8-naphthyridine-3-carboxamide; N-[4-(Isopropoxy)phenyl]-2-(trifluoromethyl)-1,8-naphthyridine-3-carboxamide; 2-(Trifluoromethyl)-N-[4-(propan-2-yloxy)phenyl]-1,8-naphthyridine-3-carboxamide; 393183-72-7; 1,8-Naphthyridine-3-carboxamide, N-[4-(1-methylethoxy)phenyl]-2-(trifluoromethyl)-; 9CI-labeled compound
EINECS	Contact for details

Quality Control

Our 1,8-Naphthyridine-3-Carboxamide derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.