Description

Carbamic Acid, [1,1-Bis(Hydroxymethyl)Propyl]-, 1,1-Dimethylethyl Ester (9Ci) is a specialized carbamate derivative with a protected amine functionality, serving as a valuable chemical building block and intermediate in advanced organic synthesis. Its molecular structure, featuring both a tert-butyl ester and hydroxymethyl groups, makes it particularly useful for constructing complex molecules where controlled reactivity and stability are paramount. This compound is essential for R&D chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is utilized to introduce specific functional groups or as a precursor to active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring carbamate or protected amino-alcohol motifs.
• Agrochemical Synthesis: Used as a precursor in the development of novel herbicides, fungicides, and insecticides, leveraging its reactive sites for structural diversification.
• Polymer Chemistry: Serves as a monomer or cross-linking agent in the production of specialty polyurethanes and other functional polymers.
• Organic Synthesis Reagent: Employed in research laboratories for the preparation of complex organic molecules, including natural product analogs and material science compounds.
• Peptide Mimetics: Useful in medicinal chemistry for creating peptide-like structures and prodrugs due to its carbamate linkage and hydroxyl groups.
• Chemical Biology Probes: Acts as a scaffold or linker in the design of molecular probes and bioconjugates for biochemical research.

Basic Information

Product Name	Carbamic Acid, [1,1-Bis(Hydroxymethyl)Propyl]-, 1,1-Dimethylethyl Ester (9Ci)
CAS No.	391678-52-7
Molecular Formula	C11H23NO4
Molecular Weight	233.31 g/mol
Synonyms	tert-Butyl N-[1,1-bis(hydroxymethyl)propyl]carbamate; 1,1-Dimethylethyl N-[1,1-bis(hydroxymethyl)propyl]carbamate; N-(tert-Butoxycarbonyl)-2,2-bis(hydroxymethyl)butan-1-amine; 2,2-Bis(hydroxymethyl)butylcarbamic acid tert-butyl ester; BOC-Protected 2,2-bis(hydroxymethyl)butylamine; tert-Butyl (2,2-bis(hydroxymethyl)butyl)carbamate; (2,2-Bis(hydroxymethyl)butyl)carbamic Acid tert-Butyl Ester
EINECS	Contact for details

Quality Control

Our production of Carbamic Acid, [1,1-Bis(Hydroxymethyl)Propyl]-, 1,1-Dimethylethyl Ester adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy. We provide detailed Certificates of Analysis (COA) with every shipment, ensuring traceability and compliance with your specific research or production requirements. Specifications can be tailored to meet cGMP standards for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent absorption of moisture from the air. Store away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.