Description

5-(Trifluoromethyl)Thieno[3,2-B]Pyridine-6-Carboxylic Acid, 2-tert-Butylhydrazide is a high-value, multifunctional heterocyclic building block designed for advanced chemical synthesis. This compound is critical for research and development in the pharmaceutical and agrochemical sectors, where its unique trifluoromethyl-thienopyridine scaffold offers significant advantages in modulating biological activity and physicochemical properties. It is primarily sought by medicinal chemists and process development scientists for creating novel active ingredients and fine-tuning molecular characteristics.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly in oncology, CNS, and anti-infective therapeutic areas.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the thienopyridine core.
• Material Science: Acts as a specialty monomer or additive for creating advanced polymers with specific electronic or surface properties.
• Chemical Biology: Employed as a molecular probe or tag in biochemical assays and diagnostic tool development due to its distinct structural motif.
• Organic Synthesis Building Block: Provides a versatile scaffold for constructing complex heterocyclic libraries for high-throughput screening (HTS) in drug discovery.
• Fluorine Chemistry: The trifluoromethyl group makes it a valuable substrate for studying fluorine introduction and its effects in medicinal chemistry.

Basic Information

Product Name	5-(Trifluoromethyl)Thieno[3,2-B]Pyridine-6-Carboxylic Acid, 2-tert-Butylhydrazide
CAS No.	390357-08-1
Molecular Formula	C13H14F3N3O2S
Molecular Weight	333.33 g/mol
Synonyms	2-tert-Butyl-5-(trifluoromethyl)thieno[3,2-b]pyridine-6-carbohydrazide; 5-(Trifluoromethyl)thieno[3,2-b]pyridine-6-carboxylic acid tert-butylhydrazide; 390357-08-1; 2-(tert-Butyl)-5-(trifluoromethyl)thieno[3,2-b]pyridine-6-carbohydrazide; Thieno[3,2-b]pyridine-6-carboxylic acid, 5-(trifluoromethyl)-, 2-(1,1-dimethylethyl)hydrazide
EINECS	Contact for details

Quality Control

Our production of 5-(Trifluoromethyl)Thieno[3,2-B]Pyridine-6-Carboxylic Acid, 2-tert-Butylhydrazide adheres to stringent quality management protocols to ensure batch-to-batch consistency and purity for critical R&D and scale-up applications. All materials are characterized using advanced analytical techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.