Description

5-(Trifluoromethyl)Thieno[3,2-B]Pyridine-6-Carboxylic Acid, Hydrazide is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused heterocyclic structure. This compound is of significant commercial interest for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory pathways.
• Agrochemical Research: Serves as a core scaffold for developing new-generation herbicides and pesticides, leveraging the stability imparted by the trifluoromethyl group.
• Material Science: Used in the research and development of specialty chemicals and advanced organic electronic materials due to its electron-deficient aromatic system.
• Chemical Synthesis: The reactive hydrazide moiety makes it a versatile reagent for constructing heterocycles like pyrazoles and triazoles via condensation reactions.

Basic Information

Product Name	5-(Trifluoromethyl)Thieno[3,2-B]Pyridine-6-Carboxylic Acid, Hydrazide
CAS No.	390357-05-8
Molecular Formula	C9H6F3N3OS
Molecular Weight	261.22 g/mol
Synonyms	5-(Trifluoromethyl)thieno[3,2-b]pyridine-6-carbohydrazide; 5-(Trifluoromethyl)-6-hydrazinylcarbonylthieno[3,2-b]pyridine; Thieno[3,2-b]pyridine-6-carboxylic acid, 5-(trifluoromethyl)-, hydrazide; 390357-05-8; 5-Trifluoromethylthieno[3,2-b]pyridine-6-carboxylic acid hydrazide
EINECS	Contact for details

Quality Control

Our production of 5-(Trifluoromethyl)Thieno[3,2-B]Pyridine-6-Carboxylic Acid, Hydrazide adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for critical R&D and scale-up processes. All materials are characterized and tested using advanced analytical techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.