Description

4-(1,4-Dioxaspiro[4.5]dec-8-yl)benzenamine is a specialized aromatic amine derivative featuring a spirocyclic ketal-protected ketone moiety, which serves as a versatile and protected synthetic intermediate. This compound is valued for its role in constructing complex molecular architectures, particularly in the synthesis of pharmaceuticals and advanced organic materials where controlled reactivity and functional group manipulation are critical. It is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the development of new active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those requiring a protected carbonyl group for subsequent selective transformations.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its amine functionality for creating bioactive molecules.
• Organic Electronics Material Precursor: Serves as a starting material for synthesizing complex organic semiconductors or charge-transport materials due to its conjugated amine structure.
• Ligand and Catalyst Development: The amine group can be functionalized to create novel chelating ligands for asymmetric catalysis or metal-organic frameworks (MOFs).
• Polymer Modification: Acts as a monomer or cross-linking agent for producing specialty polymers with specific thermal or mechanical properties.
• Academic and R&D Laboratories: Employed in methodological studies and the exploration of new organic reactions involving protected functional groups.

Basic Information

Product Name	4-(1,4-Dioxaspiro[4.5]dec-8-yl)benzenamine
CAS No.	389602-90-8
Molecular Formula	C16H21NO2
Molecular Weight	259.34 g/mol
Synonyms	4-(1,4-Dioxaspiro[4.5]dec-8-yl)aniline; 8-(4-Aminophenyl)-1,4-dioxaspiro[4.5]decane; Benzenamine, 4-(1,4-dioxaspiro[4.5]dec-8-yl)-; 4-(1,4-Dioxaspiro[4,5]decane-8-yl)aniline; 4-(8,9-Dioxaspiro[4.5]decyl)aniline; 4-Aminophenyl-1,4-dioxaspiro[4.5]decane; 4-(1,4-Dioxaspiro[4.5]decan-8-yl)benzenamine
EINECS	Contact for details

Quality Control

Our 4-(1,4-Dioxaspiro[4.5]dec-8-yl)benzenamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its sensitivity to oxidation, prolonged exposure to air should be minimized. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.