Description

Pyrrolidine, 1-[[(2R,3S)-3-Methyl-2-Aziridinyl]Carbonyl]-, Rel- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its core value lies in its unique aziridine-pyrrolidine hybrid structure, which serves as a versatile precursor for constructing complex nitrogen-containing pharmacophores. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and fine chemicals requiring precise stereochemical control.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel APIs, especially in oncology, antiviral, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where specific stereochemistry impacts biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and dyes.
• Academic and R&D Laboratories: A valuable tool for methodological studies in organic chemistry and medicinal chemistry research programs.

Basic Information

Item	Detail
Product Name	Pyrrolidine, 1-[[(2R,3S)-3-Methyl-2-Aziridinyl]Carbonyl]-, Rel- (9Ci)
CAS No.	389572-78-5
Molecular Formula	C9H16N2O
Molecular Weight	168.24 g/mol
Synonyms	rel-(2R,3S)-1-(3-Methylaziridine-2-carbonyl)pyrrolidine; 1-[(2R,3S)-3-Methylaziridine-2-carbonyl]pyrrolidine; (rel)-(2R,3S)-N-Pyrrolidinyl-3-methylaziridine-2-carboxamide; Aziridine-2-carboxamide, N-pyrrolidinyl-3-methyl-, (2R,3S)-rel-; Chiral Aziridine Pyrrolidinamide; 389572-78-5; Pyrrolidine, 1-[(3-methyl-2-aziridinyl)carbonyl]-, (2R,3S)-rel-
EINECS	Contact for details

Quality Control

Every batch of Pyrrolidine, 1-[[(2R,3S)-3-Methyl-2-Aziridinyl]Carbonyl]-, Rel- (9Ci) is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, and chiral analysis to ensure identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.