Description

1,8-Naphthyridine-3-Carboxamide,2-(Trifluoromethyl)-n-[[3-(Trifluoromethyl)Phenyl]Methyl]-(9Ci) is a specialized organic compound featuring a naphthyridine core substituted with trifluoromethyl groups, a structure of significant interest in advanced chemical synthesis. This compound matters as a high-value pharmaceutical intermediate and key building block for research into novel bioactive molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to incorporate its unique fluorinated heterocyclic scaffold into new products. The compound is supplied with CAS number 388565-57-9.

Application

This trifluoromethylated naphthyridine derivative serves as a critical precursor in several high-tech applications:

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in oncology, antiviral, and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in developing new active ingredients for crop protection agents, leveraging the bioactivity and metabolic stability imparted by the trifluoromethyl groups.
• Chemical Biology Probe: Serves as a core structure for designing molecular probes to study enzyme function and biological pathways.
• Material Science Precursor: Potential intermediate for creating advanced organic electronic materials or metal-organic frameworks (MOFs) with specific fluorinated properties.
• Process Chemistry & Scale-up: Used in route scouting and optimization for the commercial production of complex target molecules.

Basic Information

Product Name	1,8-Naphthyridine-3-Carboxamide,2-(Trifluoromethyl)-n-[[3-(Trifluoromethyl)Phenyl]Methyl]-(9Ci)
CAS No.	388565-57-9
Molecular Formula	C₁₈H₁₁F₆N₃O
Molecular Weight	399.29 g/mol
Synonyms	N-[[3-(Trifluoromethyl)phenyl]methyl]-2-(trifluoromethyl)-1,8-naphthyridine-3-carboxamide; 2-(Trifluoromethyl)-N-[[3-(trifluoromethyl)phenyl]methyl]-1,8-naphthyridine-3-carboxamide; 388565-57-9; 1,8-Naphthyridine-3-carboxamide, 2-(trifluoromethyl)-N-[[3-(trifluoromethyl)phenyl]methyl]-; SCHEMBL21805527; AKOS040759232; ZINC000253930911; A1-00826
EINECS	Contact for details

Quality Control

Our high-purity batch of 1,8-Naphthyridine-3-Carboxamide,2-(Trifluoromethyl)-n-[[3-(Trifluoromethyl)Phenyl]Methyl]-(9Ci) is produced under strict quality management protocols. Each lot undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as HPLC purity, NMR confirmation, and residual solvent levels are provided with every shipment. We support cGMP compliance for advanced intermediates and can tailor quality documentation to meet specific project or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product is light-sensitive (store away from light). Keep the container tightly sealed to protect from moisture and contamination. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.