Description

Quinoline, 6-Fluoro-1,2,3,4-Tetrahydro-1-Methyl- (9Ci) is a fluorinated tetrahydroquinoline derivative, a high-value pharmaceutical intermediate and organic building block of significant interest in modern synthetic chemistry. Its core value lies in its unique molecular scaffold, which is pivotal for constructing complex molecules with potential biological activity. This compound is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced fluorinated pesticides and herbicides, where the fluorine atom enhances biological activity and stability.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a building block for electron-transport or host materials in display and lighting technologies.
• Ligand and Catalyst Development: Employed in the synthesis of novel nitrogen-containing ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Fluorescent Probe and Dye Chemistry: Utilized as a core structure for developing sensitive fluorophores used in bio-imaging and diagnostic assays.
• Academic and Industrial Research: A valuable compound for methodological studies in organic synthesis, particularly in fluorination and heterocyclic chemistry.

Basic Information

Product Name	Quinoline, 6-Fluoro-1,2,3,4-Tetrahydro-1-Methyl- (9Ci)
CAS No.	388078-35-1
Molecular Formula	C10H12FN
Molecular Weight	165.21 g/mol
Synonyms	6-Fluoro-1-methyl-1,2,3,4-tetrahydroquinoline; 1-Methyl-6-fluoro-1,2,3,4-tetrahydroquinoline; 6-Fluoro-1-methyl-1,2,3,4-tetrahydroquinoline (9CI); 1,2,3,4-Tetrahydro-1-methyl-6-fluoroquinoline; 6-Fluoro-1-methyl-THQ; F-Me-THQ; 388078-35-1
EINECS	Contact for details

Quality Control

Our production of Quinoline, 6-Fluoro-1,2,3,4-Tetrahydro-1-Methyl- (9Ci) adheres to stringent GMP and ISO 9001 quality management principles. Every batch undergoes comprehensive analytical characterization, including HPLC for purity, GC-MS and NMR for structural confirmation, and KF titration for moisture content. A detailed Certificate of Analysis (COA) is provided with each shipment to ensure full traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.