Description

1(2H)-Quinolinecarboxaldehyde, 6-Fluoro-3,4-Dihydro- is a high-purity fluorinated quinoline derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in its unique molecular scaffold, which combines a reactive aldehyde group with a fluorinated, partially saturated quinoline core, enabling precise structural modifications. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and pesticides, leveraging the bioactivity of the fluorinated quinoline structure.
• Organic Synthesis: Serves as a versatile precursor for creating complex heterocyclic compounds, ligands for catalysis, and specialty fine chemicals.
• Material Science: Potential application in the synthesis of organic semiconductors, fluorescent dyes, and advanced polymeric materials due to its conjugated system.
• Academic & R&D: A valuable reagent for universities and contract research organizations (CROs) exploring new chemical reactions and methodologies.

Basic Information

Product Name	1(2H)-Quinolinecarboxaldehyde, 6-Fluoro-3,4-Dihydro-
CAS No.	388078-32-8
Molecular Formula	C₁₀H₈FNO
Molecular Weight	177.18 g/mol
Synonyms	6-Fluoro-3,4-dihydro-1(2H)-quinolinecarboxaldehyde; 6-Fluoro-3,4-dihydro-2H-quinoline-1-carbaldehyde; 6-Fluoro-1,2,3,4-tetrahydroquinoline-1-carboxaldehyde; 6-Fluoro-1-formyl-1,2,3,4-tetrahydroquinoline; 6-Fluoro-3,4-dihydro-2H-quinolinecarbaldehyde; 6-Fluoro-1,2,3,4-tetrahydroquinoline-1-carbaldehyde
EINECS	Contact for details

Quality Control

Every batch of 1(2H)-Quinolinecarboxaldehyde, 6-Fluoro-3,4-Dihydro- is produced under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.