Description

Cyclopropanecarboxamide, 2-[(Tetrahydro-2H-Pyran-2-Yl)Oxy]- (9Ci) is a specialized organic compound featuring a cyclopropane carboxamide core protected by a tetrahydropyranyl (THP) ether group. This molecule matters as a key pharmaceutical intermediate and protected synthon in advanced organic synthesis, offering chemists a versatile building block for constructing complex molecular architectures. It is primarily needed by R&D and production teams in the pharmaceutical, agrochemical, and fine chemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing cyclopropane motifs known for their metabolic stability and conformational rigidity.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, where the cyclopropane ring can contribute to biological activity.
• Fine Chemical Building Block: Acts as a protected amine derivative for multi-step organic synthesis in academic and industrial research laboratories.
• Methodology Development: Employed in chemical research for developing new synthetic routes involving ether protection/deprotection strategies and amide bond formation.
• Ligand and Catalyst Preparation: Utilized as a starting material for creating specialized ligands or organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	Cyclopropanecarboxamide, 2-[(Tetrahydro-2H-Pyran-2-Yl)Oxy]- (9Ci)
CAS No.	387845-22-9
Molecular Formula	C9H15NO3
Molecular Weight	185.22 g/mol
Synonyms	2-[(Tetrahydro-2H-pyran-2-yl)oxy]cyclopropanecarboxamide; 2-(Tetrahydro-2H-pyran-2-yloxy)cyclopropanecarboxamide; 2-(Oxiran-2-ylmethoxy)cyclopropanecarboxamide (related); THP-protected 2-hydroxycyclopropanecarboxamide; N-(2-(Tetrahydro-2H-pyran-2-yloxy)cyclopropyl)formamide (possible tautomer); Cyclopropanecarboxamide, 2-[(tetrahydro-2H-pyran-2-yl)oxy]-; CAS 387845-22-9.
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxamide, 2-[(Tetrahydro-2H-Pyran-2-Yl)Oxy]- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and synthesis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay purity and impurity profiles. Our quality system is designed to meet the stringent requirements of GMP environments for non-GMP starting materials and aligns with ISO quality management principles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to exclude moisture. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.