Description

3-(3-[(tert-Butoxycarbonyl)Amino]Phenyl)Propanoic Acid is a high-purity, protected amino acid derivative widely used as a critical building block in advanced organic synthesis. This compound is essential for the efficient construction of complex molecules, offering a versatile handle for peptide coupling and further functionalization. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active pharmaceutical ingredients (APIs) and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Serves as a protected amino acid building block for solid-phase and solution-phase peptide synthesis.
• Protease Inhibitor Development: Used in the research and production of protease inhibitors and other enzyme-targeting therapeutics.
• Bioconjugation: Employed in the preparation of antibody-drug conjugates (ADCs) and other bioconjugates due to its carboxylic acid functionality.
• Agrochemical Synthesis: Acts as an intermediate in the creation of novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Utilized in the development of functional polymers and advanced organic materials.

Basic Information

Product Name	3-(3-[(tert-Butoxycarbonyl)Amino]Phenyl)Propanoic Acid
CAS No.	387360-95-4
Molecular Formula	C14H19NO4
Molecular Weight	265.31 g/mol
Synonyms	3-(3-((tert-Butoxycarbonyl)amino)phenyl)propanoic acid; 3-[3-[(tert-Butoxycarbonyl)amino]phenyl]propionic Acid; Boc-3-APPA; N-Boc-3-Aminophenylpropionic Acid; (3-{[(tert-Butoxycarbonyl)amino]phenyl})propanoic Acid; 3-(3-Aminophenyl)propionic Acid tert-Butyl Carbamate; BOC-m-APPA; N-(tert-Butoxycarbonyl)-3-aminohydrocinnamic Acid
EINECS	Contact for details

Quality Control

Our 3-(3-[(tert-Butoxycarbonyl)Amino]Phenyl)Propanoic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.