Description

3-[4-(Methylsulfonyl)Phenyl]Propanoic Acid is a high-purity organic building block characterized by its phenylpropanoic acid core functionalized with a methylsulfonyl group at the para position. This compound matters as a versatile and critical intermediate in modern synthetic chemistry, enabling the development of novel active pharmaceutical ingredients and advanced materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of non-steroidal anti-inflammatory drugs (NSAIDs) and other bioactive molecules targeting inflammation and pain.
• Agrochemical Research: Used in the development of novel herbicides and fungicides, leveraging the bioisosteric properties of the methylsulfonyl group.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for advanced electronic materials due to its rigid aromatic structure and polar sulfone group.
• Polymer Modification: Employed to introduce functional side chains into polymers, enhancing properties like solubility, thermal stability, or biocompatibility.
• Chemical Biology Probe Synthesis: Utilized in creating tool compounds and probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	3-[4-(Methylsulfonyl)Phenyl]Propanoic Acid
CAS No.	387350-46-1
Molecular Formula	C10H12O4S
Molecular Weight	228.26 g/mol
Synonyms	4-(Methylsulfonyl)hydrocinnamic Acid; 3-(4-Methanesulfonylphenyl)propanoic Acid; 3-(p-Methylsulfonylphenyl)propionic Acid; Benzenepropanoic acid, 4-(methylsulfonyl)-; 4-(Methylsulfonyl)benzenepropanoic Acid; MS-PPA
EINECS	Contact for details

Quality Control

Our 3-[4-(Methylsulfonyl)Phenyl]Propanoic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed when not in use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.