Description

4-Oxo-1,2-Dihydro-4H-Pyrrolo[3,2,1-Ij]Quinoline-5-Carboxylicacid is a high-purity, advanced pharmaceutical intermediate belonging to a class of fused heterocyclic compounds. This specialized chemical is critical for the research and development of novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. It is primarily sought after by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders or with anti-inflammatory properties.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize potency, selectivity, and pharmacokinetic profiles of new chemical entities.
• Organic Synthesis: Acts as a versatile precursor for the construction of more complex polycyclic frameworks due to its reactive carboxylic acid and ketone functional groups.
• Biochemical Tool Compound: Potential use in developing fluorescent probes or enzyme inhibitors for biological assay development and target validation.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals for high-value applications in life sciences.

Basic Information

Product Name	4-Oxo-1,2-Dihydro-4H-Pyrrolo[3,2,1-Ij]Quinoline-5-Carboxylicacid
CAS No.	386715-43-1
Molecular Formula	C₁₄H₉NO₃
Molecular Weight	239.23 g/mol
Synonyms	4-Oxo-1,2-dihydro-4H-pyrrolo[3,2,1-ij]quinoline-5-carboxylic acid; 5-Carboxy-1,2-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one; Pyrroloquinolinecarboxylic acid derivative; 386715-43-1; A-867744 (research code); Fused tricyclic quinoline derivative
EINECS	Contact for details

Quality Control

Our 4-Oxo-1,2-Dihydro-4H-Pyrrolo[3,2,1-Ij]Quinoline-5-Carboxylicacid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is stable under these conditions but should be kept away from strong acids and organic solvents. For long-term storage, consider inert atmosphere packaging to prevent potential oxidation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.